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Stability of a Cosmetic Multiple Emulsion Loaded with Green Tea Extract
Multiple emulsions are excellent and exciting potential systems for the delivery of useful cosmetic agents. The work describes stability of a multiple emulsion for cosmetic purpose, loaded with extract of Camellia sinensis L. (Theaceae) in concentration of 5%. The formulation constitutes of cetyl di...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766562/ https://www.ncbi.nlm.nih.gov/pubmed/24058284 http://dx.doi.org/10.1155/2013/153695 |
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author | Mahmood, Tariq Akhtar, Naveed |
author_facet | Mahmood, Tariq Akhtar, Naveed |
author_sort | Mahmood, Tariq |
collection | PubMed |
description | Multiple emulsions are excellent and exciting potential systems for the delivery of useful cosmetic agents. The work describes stability of a multiple emulsion for cosmetic purpose, loaded with extract of Camellia sinensis L. (Theaceae) in concentration of 5%. The formulation constitutes of cetyl dimethicone copolyol and polyoxyethylene (20) cetyl ether as emulsifiers and was characterised and monitored for various physicochemical aspects. Centrifugation has no devastating effect on physical destabilization/phase separation observed for 30 days. Mean globule sizes of multiple droplets were found in the range of 10.29 ± 4.4 μm to 12.77 ± 5.1 μm and of inner droplets were in the range of 0.8 ± 0.4 μm to 1.6 ± 0.8 μm. All samples exhibited shear thinning behavior with increase in shear stress. The results of the present study indicate that multiple emulsions can be used as carrier of 5% Camellia sinensis L. extract to enhance desired effects. The developed physically and chemically stable system is an effective system for targeting skin layers; however, long-term stability at elevated temperatures may be needed with suitable modifications, if required. |
format | Online Article Text |
id | pubmed-3766562 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37665622013-09-22 Stability of a Cosmetic Multiple Emulsion Loaded with Green Tea Extract Mahmood, Tariq Akhtar, Naveed ScientificWorldJournal Research Article Multiple emulsions are excellent and exciting potential systems for the delivery of useful cosmetic agents. The work describes stability of a multiple emulsion for cosmetic purpose, loaded with extract of Camellia sinensis L. (Theaceae) in concentration of 5%. The formulation constitutes of cetyl dimethicone copolyol and polyoxyethylene (20) cetyl ether as emulsifiers and was characterised and monitored for various physicochemical aspects. Centrifugation has no devastating effect on physical destabilization/phase separation observed for 30 days. Mean globule sizes of multiple droplets were found in the range of 10.29 ± 4.4 μm to 12.77 ± 5.1 μm and of inner droplets were in the range of 0.8 ± 0.4 μm to 1.6 ± 0.8 μm. All samples exhibited shear thinning behavior with increase in shear stress. The results of the present study indicate that multiple emulsions can be used as carrier of 5% Camellia sinensis L. extract to enhance desired effects. The developed physically and chemically stable system is an effective system for targeting skin layers; however, long-term stability at elevated temperatures may be needed with suitable modifications, if required. Hindawi Publishing Corporation 2013-08-24 /pmc/articles/PMC3766562/ /pubmed/24058284 http://dx.doi.org/10.1155/2013/153695 Text en Copyright © 2013 T. Mahmood and N. Akhtar. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Mahmood, Tariq Akhtar, Naveed Stability of a Cosmetic Multiple Emulsion Loaded with Green Tea Extract |
title | Stability of a Cosmetic Multiple Emulsion Loaded with Green Tea Extract |
title_full | Stability of a Cosmetic Multiple Emulsion Loaded with Green Tea Extract |
title_fullStr | Stability of a Cosmetic Multiple Emulsion Loaded with Green Tea Extract |
title_full_unstemmed | Stability of a Cosmetic Multiple Emulsion Loaded with Green Tea Extract |
title_short | Stability of a Cosmetic Multiple Emulsion Loaded with Green Tea Extract |
title_sort | stability of a cosmetic multiple emulsion loaded with green tea extract |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766562/ https://www.ncbi.nlm.nih.gov/pubmed/24058284 http://dx.doi.org/10.1155/2013/153695 |
work_keys_str_mv | AT mahmoodtariq stabilityofacosmeticmultipleemulsionloadedwithgreenteaextract AT akhtarnaveed stabilityofacosmeticmultipleemulsionloadedwithgreenteaextract |