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Role of the eNOS-NO System in Regulating the Antiproteinuric Effects of VEGF Receptor 2 Inhibition in Diabetes
Subtle perturbations in intraglomerular VEGF/VEGFR-2 signaling or in the influencing microenvironment can profoundly affect renal function, resulting in the apparently paradoxical observation that VEGF blockade attenuates proteinuria development in experimental diabetes despite exerting the opposite...
Autores principales: | Advani, Andrew, Connelly, Kim A., Advani, Suzanne L., Thai, Kerri, Zhang, Yuan, Kelly, Darren J., Gilbert, Richard E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766587/ https://www.ncbi.nlm.nih.gov/pubmed/24063000 http://dx.doi.org/10.1155/2013/201475 |
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