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Rapid Purification and Procoagulant and Platelet Aggregating Activities of Rhombeobin: A Thrombin-Like/Gyroxin-Like Enzyme from Lachesis muta rhombeata Snake Venom
We report a rapid purification method using one-step chromatography of SVSP Rhombeobin (LMR-47) from Lachesis muta rhombeata venom and its procoagulant activities and effects on platelet aggregation. The venom was fractionated by a single chromatographic step in RP-HPLC on a C8 Discovery BIO Wide Po...
Autores principales: | Torres-Huaco, Frank Denis, Werneck, Cláudio C., Vicente, Cristina Pontes, Vassequi-Silva, Talita, Nery-Diez, Ana Cláudia Coelho, Mendes, Camila B., Antunes, Edson, Marangoni, Sérgio, Damico, Daniela C. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766598/ https://www.ncbi.nlm.nih.gov/pubmed/24058917 http://dx.doi.org/10.1155/2013/903292 |
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