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Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein
Glutathione S-transferase (GST) is the key enzyme in multidrug resistance (MDR) of tumour. Inhibition of the expression or activity of GST has emerged as a promising therapeutic strategy for the reversal of MDR. Coniferyl ferulate (CF), isolated from the root of Angelica sinensis (Oliv.) Diels (Radi...
Autores principales: | Chen, Chang, Wu, Chuanhong, Lu, Xinhua, Yan, Zhiyong, Gao, Jian, Zhao, Hui, Li, Shaojing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766616/ https://www.ncbi.nlm.nih.gov/pubmed/24058374 http://dx.doi.org/10.1155/2013/639083 |
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