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The Cost-Utility Analysis of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma in Iran

BACKGROUND: PET scan is a non-invasive, complex and expensive medical imaging technology that is normally used for the diagnosis and treatment of various diseases including lung cancer. OBJECTIVES: The purpose of this study is to assess the cost effectiveness of this technology in the diagnosis and...

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Autores principales: Akbari Sari, Ali, Ravaghi, Hamid, Mobinizadeh, Mohammadreza, Sarvari, Sima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767016/
https://www.ncbi.nlm.nih.gov/pubmed/24046780
http://dx.doi.org/10.5812/iranjradiol.8559
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author Akbari Sari, Ali
Ravaghi, Hamid
Mobinizadeh, Mohammadreza
Sarvari, Sima
author_facet Akbari Sari, Ali
Ravaghi, Hamid
Mobinizadeh, Mohammadreza
Sarvari, Sima
author_sort Akbari Sari, Ali
collection PubMed
description BACKGROUND: PET scan is a non-invasive, complex and expensive medical imaging technology that is normally used for the diagnosis and treatment of various diseases including lung cancer. OBJECTIVES: The purpose of this study is to assess the cost effectiveness of this technology in the diagnosis and treatment of non- small cell lung carcinoma (NSCLC) in Iran. MATERIALS AND METHODS: The main electronic databases including The Cochrane Library and Medline were searched to identify available evidence about the performance and effectiveness of technology. A standard decision tree model with seven strategies was used to perform the economic evaluation. Retrieved studies and expert opinion were used to estimate the cost of each treatment strategy in Iran. The costs were divided into three categories including capital costs (depreciation costs of buildings and equipment), staff costs and other expenses (including cost of consumables, running and maintenance costs). The costs were estimated in both IR-Rials and US-Dollars with an exchange rate of 10.000 IR Rials per one US Dollar according to the exchange rate in 2008. RESULTS: The total annual running cost of a PET scan was about 8850 to 13000 million Rials, (0.9 to 1.3 million US$). The average cost of performing a PET scan varied between 3 and 4.5 million Rials (300 to 450US$). The strategies 3 (mediastinoscopy alone) and 7 (mediastinoscopy after PET scan) were more cost-effective than other strategies, especially when the result of the CT-scan performed before PET scan was negative. CONCLUSION: The technical performance of PET scan is significantly higher than similar technologies for staging and treatment of NSCLC. In addition, it might slightly improve the treatment process and lead to a small level of increase in the quality adjusted life year (QALY) gained by these patients making it cost-effective for the treatment of NSCLC.
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spelling pubmed-37670162013-09-17 The Cost-Utility Analysis of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma in Iran Akbari Sari, Ali Ravaghi, Hamid Mobinizadeh, Mohammadreza Sarvari, Sima Iran J Radiol Chest Imaging BACKGROUND: PET scan is a non-invasive, complex and expensive medical imaging technology that is normally used for the diagnosis and treatment of various diseases including lung cancer. OBJECTIVES: The purpose of this study is to assess the cost effectiveness of this technology in the diagnosis and treatment of non- small cell lung carcinoma (NSCLC) in Iran. MATERIALS AND METHODS: The main electronic databases including The Cochrane Library and Medline were searched to identify available evidence about the performance and effectiveness of technology. A standard decision tree model with seven strategies was used to perform the economic evaluation. Retrieved studies and expert opinion were used to estimate the cost of each treatment strategy in Iran. The costs were divided into three categories including capital costs (depreciation costs of buildings and equipment), staff costs and other expenses (including cost of consumables, running and maintenance costs). The costs were estimated in both IR-Rials and US-Dollars with an exchange rate of 10.000 IR Rials per one US Dollar according to the exchange rate in 2008. RESULTS: The total annual running cost of a PET scan was about 8850 to 13000 million Rials, (0.9 to 1.3 million US$). The average cost of performing a PET scan varied between 3 and 4.5 million Rials (300 to 450US$). The strategies 3 (mediastinoscopy alone) and 7 (mediastinoscopy after PET scan) were more cost-effective than other strategies, especially when the result of the CT-scan performed before PET scan was negative. CONCLUSION: The technical performance of PET scan is significantly higher than similar technologies for staging and treatment of NSCLC. In addition, it might slightly improve the treatment process and lead to a small level of increase in the quality adjusted life year (QALY) gained by these patients making it cost-effective for the treatment of NSCLC. Kowsar 2013-05-20 2013-06 /pmc/articles/PMC3767016/ /pubmed/24046780 http://dx.doi.org/10.5812/iranjradiol.8559 Text en Copyright © 2013, Tehran University of Medical Sciences and Iranian Society of Radiology http://creativecommons.org/licenses/by/3/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chest Imaging
Akbari Sari, Ali
Ravaghi, Hamid
Mobinizadeh, Mohammadreza
Sarvari, Sima
The Cost-Utility Analysis of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma in Iran
title The Cost-Utility Analysis of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma in Iran
title_full The Cost-Utility Analysis of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma in Iran
title_fullStr The Cost-Utility Analysis of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma in Iran
title_full_unstemmed The Cost-Utility Analysis of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma in Iran
title_short The Cost-Utility Analysis of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma in Iran
title_sort cost-utility analysis of pet-scan in diagnosis and treatment of non-small cell lung carcinoma in iran
topic Chest Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767016/
https://www.ncbi.nlm.nih.gov/pubmed/24046780
http://dx.doi.org/10.5812/iranjradiol.8559
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