Cargando…

Deceit and Transparency in Placebo Research

Studies designed to elicit the full strength of the placebo effect differ from those in which the placebo effect represents a nuisance factor to be accounted for in order to establish the efficacy of a treatment. In the latter, informed consent is the rule; in the first, while consent may be informe...

Descripción completa

Detalles Bibliográficos
Autor principal: Justman, Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767217/
https://www.ncbi.nlm.nih.gov/pubmed/24058307
_version_ 1782283632762683392
author Justman, Stewart
author_facet Justman, Stewart
author_sort Justman, Stewart
collection PubMed
description Studies designed to elicit the full strength of the placebo effect differ from those in which the placebo effect represents a nuisance factor to be accounted for in order to establish the efficacy of a treatment. In the latter, informed consent is the rule; in the first, while consent may be informed in some narrow sense of the word, deception is common. However, the trickery of placebo experimentation goes beyond straightforward lies to include the use of crafty ambiguities, half-truths, and deliberate omissions in scripts read to the subjects of these studies. As words come to resemble therapeutic agents in their own right, it is only to be expected that researchers would methodically exploit verbal effects to evoke the responses they are looking for. Even experiments in which placebo is disclosed as placebo have used language in leading and misleading ways. Such studies are conducted in the hope of yielding results that might translate into clinical practice, but it should be noted that good clinical practice has a placebo value of its own — that is, confers a benefit over and beyond the specific effects of treatments — even if nothing like a sugar pill is administered.
format Online
Article
Text
id pubmed-3767217
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher YJBM
record_format MEDLINE/PubMed
spelling pubmed-37672172013-09-20 Deceit and Transparency in Placebo Research Justman, Stewart Yale J Biol Med Focus: Research and Clinical Ethics Studies designed to elicit the full strength of the placebo effect differ from those in which the placebo effect represents a nuisance factor to be accounted for in order to establish the efficacy of a treatment. In the latter, informed consent is the rule; in the first, while consent may be informed in some narrow sense of the word, deception is common. However, the trickery of placebo experimentation goes beyond straightforward lies to include the use of crafty ambiguities, half-truths, and deliberate omissions in scripts read to the subjects of these studies. As words come to resemble therapeutic agents in their own right, it is only to be expected that researchers would methodically exploit verbal effects to evoke the responses they are looking for. Even experiments in which placebo is disclosed as placebo have used language in leading and misleading ways. Such studies are conducted in the hope of yielding results that might translate into clinical practice, but it should be noted that good clinical practice has a placebo value of its own — that is, confers a benefit over and beyond the specific effects of treatments — even if nothing like a sugar pill is administered. YJBM 2013-09-20 /pmc/articles/PMC3767217/ /pubmed/24058307 Text en Copyright ©2013, Yale Journal of Biology and Medicine https://creativecommons.org/licenses/by-nc/3.0/This is an open access article distributed under the terms of the Creative Commons CC BY-NC license, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use the material for commercial purposes.
spellingShingle Focus: Research and Clinical Ethics
Justman, Stewart
Deceit and Transparency in Placebo Research
title Deceit and Transparency in Placebo Research
title_full Deceit and Transparency in Placebo Research
title_fullStr Deceit and Transparency in Placebo Research
title_full_unstemmed Deceit and Transparency in Placebo Research
title_short Deceit and Transparency in Placebo Research
title_sort deceit and transparency in placebo research
topic Focus: Research and Clinical Ethics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767217/
https://www.ncbi.nlm.nih.gov/pubmed/24058307
work_keys_str_mv AT justmanstewart deceitandtransparencyinplaceboresearch