New Way of Direct Nitrogen Atom Phenylation in Quinoline Derivatives

Comparison of ion-molecular reactions of free-phenyl cations generated by tritium β-decay with 2-methyl- and 2-phenylquinolines has been investigated. The reaction of direct nitrogen atom phenylation with the help of nucleogenic phenyl cations has been fulfilled for the first time and a new one-step...

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Detalles Bibliográficos
Autores principales: Shchepina, Nadezhda E., Avrorin, Viktor V., Badun, Gennady A., Lewis, Scott B., Shurov, Sergey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767319/
https://www.ncbi.nlm.nih.gov/pubmed/24052846
http://dx.doi.org/10.5402/2012/526867
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author Shchepina, Nadezhda E.
Avrorin, Viktor V.
Badun, Gennady A.
Lewis, Scott B.
Shurov, Sergey N.
author_facet Shchepina, Nadezhda E.
Avrorin, Viktor V.
Badun, Gennady A.
Lewis, Scott B.
Shurov, Sergey N.
author_sort Shchepina, Nadezhda E.
collection PubMed
description Comparison of ion-molecular reactions of free-phenyl cations generated by tritium β-decay with 2-methyl- and 2-phenylquinolines has been investigated. The reaction of direct nitrogen atom phenylation with the help of nucleogenic phenyl cations has been fulfilled for the first time and a new one-step synthesis of tritium-labeled N-phenyl-2-phenylquinolinium salt—lipophilic radioactive biological marker has been elaborated.
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spelling pubmed-37673192013-09-19 New Way of Direct Nitrogen Atom Phenylation in Quinoline Derivatives Shchepina, Nadezhda E. Avrorin, Viktor V. Badun, Gennady A. Lewis, Scott B. Shurov, Sergey N. ISRN Org Chem Research Article Comparison of ion-molecular reactions of free-phenyl cations generated by tritium β-decay with 2-methyl- and 2-phenylquinolines has been investigated. The reaction of direct nitrogen atom phenylation with the help of nucleogenic phenyl cations has been fulfilled for the first time and a new one-step synthesis of tritium-labeled N-phenyl-2-phenylquinolinium salt—lipophilic radioactive biological marker has been elaborated. International Scholarly Research Network 2012-07-03 /pmc/articles/PMC3767319/ /pubmed/24052846 http://dx.doi.org/10.5402/2012/526867 Text en Copyright © 2012 Nadezhda E. Shchepina et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Shchepina, Nadezhda E.
Avrorin, Viktor V.
Badun, Gennady A.
Lewis, Scott B.
Shurov, Sergey N.
New Way of Direct Nitrogen Atom Phenylation in Quinoline Derivatives
title New Way of Direct Nitrogen Atom Phenylation in Quinoline Derivatives
title_full New Way of Direct Nitrogen Atom Phenylation in Quinoline Derivatives
title_fullStr New Way of Direct Nitrogen Atom Phenylation in Quinoline Derivatives
title_full_unstemmed New Way of Direct Nitrogen Atom Phenylation in Quinoline Derivatives
title_short New Way of Direct Nitrogen Atom Phenylation in Quinoline Derivatives
title_sort new way of direct nitrogen atom phenylation in quinoline derivatives
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767319/
https://www.ncbi.nlm.nih.gov/pubmed/24052846
http://dx.doi.org/10.5402/2012/526867
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