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A Convenient, TiCl(4)/SnCl(4)-Mediated Synthesis of N-Phenyl or N-Aryl Benzamidines and N-Phenylpicolinamidines

A new, TiCl(4)-or SnCl(4)-mediated, solvent-free method was developed for the synthesis of N-Aryl benzamidines and N-phenylpicolinamidines, in moderate-to-good yield, using suitable amines and nitriles as starting materials.

Detalles Bibliográficos
Autores principales: Patil, Umesh D., Mahulikar, Pramod P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767339/
https://www.ncbi.nlm.nih.gov/pubmed/24052858
http://dx.doi.org/10.5402/2012/963195
Descripción
Sumario:A new, TiCl(4)-or SnCl(4)-mediated, solvent-free method was developed for the synthesis of N-Aryl benzamidines and N-phenylpicolinamidines, in moderate-to-good yield, using suitable amines and nitriles as starting materials.