Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Their Corresponding 2(1H)Thiones Using Trichloroacetic Acid as a Catalyst under Solvent-Free Conditions

Trichloroacetic acid was found to be a convenient catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones and their corresponding 2(1H)-thiones through a one-pot three-component reaction of aldehydes, alkyl acetoacetate, and urea or thiourea at 70°C under solvent-free conditions.

Detalles Bibliográficos
Autores principales: Karimi-Jaberi, Zahed, Moaddeli, Mohammad Sadegh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767353/
https://www.ncbi.nlm.nih.gov/pubmed/24052844
http://dx.doi.org/10.5402/2012/474626
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author Karimi-Jaberi, Zahed
Moaddeli, Mohammad Sadegh
author_facet Karimi-Jaberi, Zahed
Moaddeli, Mohammad Sadegh
author_sort Karimi-Jaberi, Zahed
collection PubMed
description Trichloroacetic acid was found to be a convenient catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones and their corresponding 2(1H)-thiones through a one-pot three-component reaction of aldehydes, alkyl acetoacetate, and urea or thiourea at 70°C under solvent-free conditions.
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spelling pubmed-37673532013-09-19 Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Their Corresponding 2(1H)Thiones Using Trichloroacetic Acid as a Catalyst under Solvent-Free Conditions Karimi-Jaberi, Zahed Moaddeli, Mohammad Sadegh ISRN Org Chem Research Article Trichloroacetic acid was found to be a convenient catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones and their corresponding 2(1H)-thiones through a one-pot three-component reaction of aldehydes, alkyl acetoacetate, and urea or thiourea at 70°C under solvent-free conditions. International Scholarly Research Network 2012-10-15 /pmc/articles/PMC3767353/ /pubmed/24052844 http://dx.doi.org/10.5402/2012/474626 Text en Copyright © 2012 Z. Karimi-Jaberi and M. S. Moaddeli. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Karimi-Jaberi, Zahed
Moaddeli, Mohammad Sadegh
Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Their Corresponding 2(1H)Thiones Using Trichloroacetic Acid as a Catalyst under Solvent-Free Conditions
title Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Their Corresponding 2(1H)Thiones Using Trichloroacetic Acid as a Catalyst under Solvent-Free Conditions
title_full Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Their Corresponding 2(1H)Thiones Using Trichloroacetic Acid as a Catalyst under Solvent-Free Conditions
title_fullStr Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Their Corresponding 2(1H)Thiones Using Trichloroacetic Acid as a Catalyst under Solvent-Free Conditions
title_full_unstemmed Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Their Corresponding 2(1H)Thiones Using Trichloroacetic Acid as a Catalyst under Solvent-Free Conditions
title_short Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Their Corresponding 2(1H)Thiones Using Trichloroacetic Acid as a Catalyst under Solvent-Free Conditions
title_sort synthesis of 3,4-dihydropyrimidin-2(1h)-ones and their corresponding 2(1h)thiones using trichloroacetic acid as a catalyst under solvent-free conditions
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767353/
https://www.ncbi.nlm.nih.gov/pubmed/24052844
http://dx.doi.org/10.5402/2012/474626
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