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Ferric Hydrogensulfate [Fe(HSO(4))(3)] As a Reusable Heterogeneous Catalyst for the Synthesis of 5-Substituted-1H-Tetrazoles and Amides
Ferric hydrogensulfate catalyzed the synthesis of 5-substituted 1H-tetrazoles via [2 + 3] cycloaddition of nitriles and sodium azide. This method has the advantages of high yields, simple methodology, and easy workup. The catalyst can be recovered by simple filtration and reused delivering good yiel...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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International Scholarly Research Network
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767363/ https://www.ncbi.nlm.nih.gov/pubmed/24052817 http://dx.doi.org/10.5402/2011/195850 |
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author | Eshghi, Hossein Seyedi, Seyed Mohammad Zarei, Elaheh Rahimi |
author_facet | Eshghi, Hossein Seyedi, Seyed Mohammad Zarei, Elaheh Rahimi |
author_sort | Eshghi, Hossein |
collection | PubMed |
description | Ferric hydrogensulfate catalyzed the synthesis of 5-substituted 1H-tetrazoles via [2 + 3] cycloaddition of nitriles and sodium azide. This method has the advantages of high yields, simple methodology, and easy workup. The catalyst can be recovered by simple filtration and reused delivering good yields. Also, ferric hydrogensulfate catalyzed the hydrolysis of nitriles to primary amides under aqueous conditions. Various aliphatic and aromatic nitriles converted to the corresponding amides in good yields without any contamination with carboxylic acids. |
format | Online Article Text |
id | pubmed-3767363 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Scholarly Research Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-37673632013-09-19 Ferric Hydrogensulfate [Fe(HSO(4))(3)] As a Reusable Heterogeneous Catalyst for the Synthesis of 5-Substituted-1H-Tetrazoles and Amides Eshghi, Hossein Seyedi, Seyed Mohammad Zarei, Elaheh Rahimi ISRN Org Chem Research Article Ferric hydrogensulfate catalyzed the synthesis of 5-substituted 1H-tetrazoles via [2 + 3] cycloaddition of nitriles and sodium azide. This method has the advantages of high yields, simple methodology, and easy workup. The catalyst can be recovered by simple filtration and reused delivering good yields. Also, ferric hydrogensulfate catalyzed the hydrolysis of nitriles to primary amides under aqueous conditions. Various aliphatic and aromatic nitriles converted to the corresponding amides in good yields without any contamination with carboxylic acids. International Scholarly Research Network 2011-03-29 /pmc/articles/PMC3767363/ /pubmed/24052817 http://dx.doi.org/10.5402/2011/195850 Text en Copyright © 2011 Hossein Eshghi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Eshghi, Hossein Seyedi, Seyed Mohammad Zarei, Elaheh Rahimi Ferric Hydrogensulfate [Fe(HSO(4))(3)] As a Reusable Heterogeneous Catalyst for the Synthesis of 5-Substituted-1H-Tetrazoles and Amides |
title | Ferric Hydrogensulfate [Fe(HSO(4))(3)] As a Reusable Heterogeneous Catalyst for the Synthesis of 5-Substituted-1H-Tetrazoles and Amides |
title_full | Ferric Hydrogensulfate [Fe(HSO(4))(3)] As a Reusable Heterogeneous Catalyst for the Synthesis of 5-Substituted-1H-Tetrazoles and Amides |
title_fullStr | Ferric Hydrogensulfate [Fe(HSO(4))(3)] As a Reusable Heterogeneous Catalyst for the Synthesis of 5-Substituted-1H-Tetrazoles and Amides |
title_full_unstemmed | Ferric Hydrogensulfate [Fe(HSO(4))(3)] As a Reusable Heterogeneous Catalyst for the Synthesis of 5-Substituted-1H-Tetrazoles and Amides |
title_short | Ferric Hydrogensulfate [Fe(HSO(4))(3)] As a Reusable Heterogeneous Catalyst for the Synthesis of 5-Substituted-1H-Tetrazoles and Amides |
title_sort | ferric hydrogensulfate [fe(hso(4))(3)] as a reusable heterogeneous catalyst for the synthesis of 5-substituted-1h-tetrazoles and amides |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767363/ https://www.ncbi.nlm.nih.gov/pubmed/24052817 http://dx.doi.org/10.5402/2011/195850 |
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