Hsp60 Chaperonin Acts as Barrier to Pharmacologically Induced Oxidative Stress Mediated Apoptosis in Tumor Cells with Differential Stress Response

Mitochondrial functions play a central role in energy metabolism and provide survival fitness to both normal and tumor cells. Mitochondrial chaperonin Hsp60 is involved in both pro- and anti-apoptotic functions, but how Hsp60 senses the mitochondria selective oxidative stress response is unknown. In...

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Detalles Bibliográficos
Autores principales: Sarangi, Upasana, Singh, Manish Kumar, Abhijnya, Kanugovi Vijaya Vittal, Reddy, Lebaka Prasanna Anjaneya, Prasad, Badabagni Siva, Pitke, Vikrant Vinay, Paithankar, Khanderao, Sreedhar, Amere Subbarao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767580/
https://www.ncbi.nlm.nih.gov/pubmed/24027419
http://dx.doi.org/10.4137/DTI.S12513

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