Cargando…

Additional Sex Combs-Like 2 Is Required for Polycomb Repressive Complex 2 Binding at Select Targets

Polycomb Group (PcG) proteins are epigenetic repressors of gene expression. The Drosophila Additional sex combs (Asx) gene and its mammalian homologs exhibit PcG function in genetic assays; however, the mechanism by which Asx family proteins mediate gene repression is not well understood. ASXL2, one...

Descripción completa

Detalles Bibliográficos
Autores principales: Lai, Hsiao-Lei, Wang, Q. Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767597/
https://www.ncbi.nlm.nih.gov/pubmed/24040135
http://dx.doi.org/10.1371/journal.pone.0073983