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An Improved Quantitative Approach for the Assessment of Mitochondrial Fragmentation in Chemoresistant Ovarian Cancer Cells
Mitochondrial fission is a process that involves cleavage of mitochondria into smaller fragments and is regulated by the GTPase Dynamin-related protein 1 (Drp1). Higher levels of mitochondrial fission are associated with the induction of apoptosis in cancer cells. However, current methods to accurat...
Autores principales: | Farrand, Lee, Kim, Ji Young, Im-Aram, Akechai, Suh, Jeong-Yong, Lee, Hyong Joo, Tsang, Benjamin K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767598/ https://www.ncbi.nlm.nih.gov/pubmed/24040144 http://dx.doi.org/10.1371/journal.pone.0074008 |
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