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Depletion of the p43 Mitochondrial T3 Receptor Increases Sertoli Cell Proliferation in Mice

Among T3 receptors, TRα1 is ubiquitous and its deletion or a specific expression of a dominant-negative TRα1 isoform in Sertoli cell leads to an increase in testis weight and sperm production. The identification of a 43-kDa truncated form of the nuclear receptor TRα1 (p43) in the mitochondrial matri...

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Detalles Bibliográficos
Autores principales: Fumel, Betty, Roy, Stéphanie, Fouchécourt, Sophie, Livera, Gabriel, Parent, Anne-Simone, Casas, François, Guillou, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767600/
https://www.ncbi.nlm.nih.gov/pubmed/24040148
http://dx.doi.org/10.1371/journal.pone.0074015