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C22:0- and C24:0-dihydroceramides Confer Mixed Cytotoxicity in T-Cell Acute Lymphoblastic Leukemia Cell Lines

We previously reported that fenretinide (4-HPR) was cytotoxic to acute lymphoblastic leukemia (ALL) cell lines in vitro in association with increased levels of de novo synthesized dihydroceramides, the immediate precursors of ceramides. However, the cytotoxic potentials of native dihydroceramides ha...

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Detalles Bibliográficos
Autores principales:	Holliday Jr., Michael W., Cox, Stephen B., Kang, Min H., Maurer, Barry J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767634/ https://www.ncbi.nlm.nih.gov/pubmed/24040340 http://dx.doi.org/10.1371/journal.pone.0074768

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