Eight Nucleotide Substitutions Inhibit Splicing to HPV-16 3′-Splice Site SA3358 and Reduce the Efficiency by which HPV-16 Increases the Life Span of Primary Human Keratinocytes

The most commonly used 3′-splice site on the human papillomavirus type 16 (HPV-16) genome named SA3358 is used to produce HPV-16 early mRNAs encoding E4, E5, E6 and E7, and late mRNAs encoding L1 and L2. We have previously shown that SA3358 is suboptimal and is totally dependent on a downstream spli...

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Detalles Bibliográficos
Autores principales: Li, Xiaoze, Johansson, Cecilia, Cardoso Palacios, Carlos, Mossberg, Anki, Dhanjal, Soniya, Bergvall, Monika, Schwartz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767658/
https://www.ncbi.nlm.nih.gov/pubmed/24039800
http://dx.doi.org/10.1371/journal.pone.0072776

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