Cargando…

Effects of Indoleamine 2,3-Dioxygenase Deficiency on High-Fat Diet-Induced Hepatic Inflammation

Hepatic immune regulation is associated with the progression from simple steatosis to non-alcoholic steatohepatitis, a severe condition of inflamed fatty liver. Indoleamine 2,3-dioxygenase (IDO), an intracellular enzyme that mediates the catabolism of L-tryptophan to L-kynurenine, plays an important...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagano, Junji, Shimizu, Masahito, Hara, Takeshi, Shirakami, Yohei, Kochi, Takahiro, Nakamura, Nobuhiko, Ohtaki, Hirofumi, Ito, Hiroyasu, Tanaka, Takuji, Tsurumi, Hisashi, Saito, Kuniaki, Seishima, Mitsuru, Moriwaki, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767792/
https://www.ncbi.nlm.nih.gov/pubmed/24039933
http://dx.doi.org/10.1371/journal.pone.0073404