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Cholesterol Oxidase Is Indispensable in the Pathogenesis of Mycobacterium tuberculosis
Despite considerable research effort, the molecular mechanisms of Mycobacterium tuberculosis (Mtb) virulence remain unclear. Cholesterol oxidase (ChoD), an extracellular enzyme capable of converting cholesterol to its 3-keto-4-ene derivative, cholestenone, has been proposed to play a role in the vir...
Autores principales: | Klink, Magdalena, Brzezinska, Marta, Szulc, Izabela, Brzostek, Anna, Kielbik, Michal, Sulowska, Zofia, Dziadek, Jaroslaw |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767793/ https://www.ncbi.nlm.nih.gov/pubmed/24039915 http://dx.doi.org/10.1371/journal.pone.0073333 |
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