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Neural Mechanisms of Age-Related Slowing: The ΔCBF/ΔCMRO(2) Ratio Mediates Age-Differences in BOLD Signal and Human Performance
The precise mechanisms that give rise to the blood-oxygen-level-dependent (BOLD) activation differences that accompany age-related cognitive slowing remain fundamentally unknown. We sought to isolate the origin of age-related BOLD changes by comparing blood-flow and oxygen-metabolic constituents of...
Autores principales: | Hutchison, Joanna L., Lu, Hanzhang, Rypma, Bart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767961/ https://www.ncbi.nlm.nih.gov/pubmed/22879349 http://dx.doi.org/10.1093/cercor/bhs233 |
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