Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease

Both diabetes and periodontitis are chronic diseases. Diabetes has many adverse effects on the periodontium, and conversely periodontitis may have deleterious effects further aggravating the condition in diabetics. The potential common pathophysiologic pathways include those associated with inflamma...

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Detalles Bibliográficos
Autores principales: Grover, Harpreet Singh, Luthra, Shailly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768178/
https://www.ncbi.nlm.nih.gov/pubmed/24049328
http://dx.doi.org/10.4103/0972-124X.115642
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author Grover, Harpreet Singh
Luthra, Shailly
author_facet Grover, Harpreet Singh
Luthra, Shailly
author_sort Grover, Harpreet Singh
collection PubMed
description Both diabetes and periodontitis are chronic diseases. Diabetes has many adverse effects on the periodontium, and conversely periodontitis may have deleterious effects further aggravating the condition in diabetics. The potential common pathophysiologic pathways include those associated with inflammation, altered host responses, altered tissue homeostasis, and insulin resistance. This review examines the relationship that exists between periodontal diseases and diabetes mellitus with a focus on potential common pathophysiologic mechanisms.
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spelling pubmed-37681782013-09-18 Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease Grover, Harpreet Singh Luthra, Shailly J Indian Soc Periodontol Review Article Both diabetes and periodontitis are chronic diseases. Diabetes has many adverse effects on the periodontium, and conversely periodontitis may have deleterious effects further aggravating the condition in diabetics. The potential common pathophysiologic pathways include those associated with inflammation, altered host responses, altered tissue homeostasis, and insulin resistance. This review examines the relationship that exists between periodontal diseases and diabetes mellitus with a focus on potential common pathophysiologic mechanisms. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3768178/ /pubmed/24049328 http://dx.doi.org/10.4103/0972-124X.115642 Text en Copyright: © Journal of Indian Society of Periodontology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Grover, Harpreet Singh
Luthra, Shailly
Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease
title Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease
title_full Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease
title_fullStr Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease
title_full_unstemmed Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease
title_short Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease
title_sort molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768178/
https://www.ncbi.nlm.nih.gov/pubmed/24049328
http://dx.doi.org/10.4103/0972-124X.115642
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