Cargando…
Periodontitis, diabetes mellitus, and the lopsided redox balance: A unifying axis
AIM: The aim of present study was to evaluate and compare the total antioxidant capacity in the saliva of type 2 diabetes mellitus (DM) patients and healthy subjects, with and without periodontal disease. MATERIALS AND METHODS: The study was designed as a case–control study, comprising of 120 male s...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768185/ https://www.ncbi.nlm.nih.gov/pubmed/24049335 http://dx.doi.org/10.4103/0972-124X.115661 |
_version_ | 1782283745214070784 |
---|---|
author | Pendyala, Gowri Thomas, Biju Joshi, Saurabh |
author_facet | Pendyala, Gowri Thomas, Biju Joshi, Saurabh |
author_sort | Pendyala, Gowri |
collection | PubMed |
description | AIM: The aim of present study was to evaluate and compare the total antioxidant capacity in the saliva of type 2 diabetes mellitus (DM) patients and healthy subjects, with and without periodontal disease. MATERIALS AND METHODS: The study was designed as a case–control study, comprising of 120 male subjects, who were divided into four groups of 30 patients each. Group I: Thirty type 2 diabetic males with periodontal disease; Group II: Thirty type 2 diabetic males without periodontal disease; Group III: Thirty healthy males with periodontal disease; Group IV: Thirty healthy males without periodontal disease. After clinical measurement and sampling, the total antioxidant capacities in the saliva of type 2 diabetic and healthy men were determined, and the data were tested by non-parametric tests. The total antioxidant capacity of the clinical samples was determined spectrophotometrically. RESULTS: The total antioxidant capacity in the saliva was the lowest in type 2 diabetic males with periodontal disease. The results were statistically significant. CONCLUSION: The findings of our study finally conclude that the salivary total antioxidant capacity is affected in type 2 diabetic males, in addition to the impact of periodontal disease, and hence, can be used as a useful marker of periodontitis in healthy and diabetic patients. |
format | Online Article Text |
id | pubmed-3768185 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-37681852013-09-18 Periodontitis, diabetes mellitus, and the lopsided redox balance: A unifying axis Pendyala, Gowri Thomas, Biju Joshi, Saurabh J Indian Soc Periodontol Original Article AIM: The aim of present study was to evaluate and compare the total antioxidant capacity in the saliva of type 2 diabetes mellitus (DM) patients and healthy subjects, with and without periodontal disease. MATERIALS AND METHODS: The study was designed as a case–control study, comprising of 120 male subjects, who were divided into four groups of 30 patients each. Group I: Thirty type 2 diabetic males with periodontal disease; Group II: Thirty type 2 diabetic males without periodontal disease; Group III: Thirty healthy males with periodontal disease; Group IV: Thirty healthy males without periodontal disease. After clinical measurement and sampling, the total antioxidant capacities in the saliva of type 2 diabetic and healthy men were determined, and the data were tested by non-parametric tests. The total antioxidant capacity of the clinical samples was determined spectrophotometrically. RESULTS: The total antioxidant capacity in the saliva was the lowest in type 2 diabetic males with periodontal disease. The results were statistically significant. CONCLUSION: The findings of our study finally conclude that the salivary total antioxidant capacity is affected in type 2 diabetic males, in addition to the impact of periodontal disease, and hence, can be used as a useful marker of periodontitis in healthy and diabetic patients. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3768185/ /pubmed/24049335 http://dx.doi.org/10.4103/0972-124X.115661 Text en Copyright: © Journal of Indian Society of Periodontology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Pendyala, Gowri Thomas, Biju Joshi, Saurabh Periodontitis, diabetes mellitus, and the lopsided redox balance: A unifying axis |
title | Periodontitis, diabetes mellitus, and the lopsided redox balance: A unifying axis |
title_full | Periodontitis, diabetes mellitus, and the lopsided redox balance: A unifying axis |
title_fullStr | Periodontitis, diabetes mellitus, and the lopsided redox balance: A unifying axis |
title_full_unstemmed | Periodontitis, diabetes mellitus, and the lopsided redox balance: A unifying axis |
title_short | Periodontitis, diabetes mellitus, and the lopsided redox balance: A unifying axis |
title_sort | periodontitis, diabetes mellitus, and the lopsided redox balance: a unifying axis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768185/ https://www.ncbi.nlm.nih.gov/pubmed/24049335 http://dx.doi.org/10.4103/0972-124X.115661 |
work_keys_str_mv | AT pendyalagowri periodontitisdiabetesmellitusandthelopsidedredoxbalanceaunifyingaxis AT thomasbiju periodontitisdiabetesmellitusandthelopsidedredoxbalanceaunifyingaxis AT joshisaurabh periodontitisdiabetesmellitusandthelopsidedredoxbalanceaunifyingaxis |