Lectin staining patterns in human gastric mucosae with and without exposure to Helicobacter pylori

The aim of the present study was to evaluate qualitative changes in the glycoconjugate expression in human gastric tissue of positive and negative patients for Helicobacter pylori, through lectins: Wheat Germ Agglutinin (WGA) and Concanavalin A (Con A). The lectins recognized differently the glycoco...

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Detalles Bibliográficos
Autores principales: Melo-Junior, Mario R., Cavalcanti, Carmelita L.B., Pontes-Filho, Nicodemos T., Carvalho Jr, Luiz B., Beltrão, Eduardo I. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Microbiologia 2008
Materias:
Medical Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768390/
https://www.ncbi.nlm.nih.gov/pubmed/24031208
http://dx.doi.org/10.1590/S1517-83822008000200007
Descripción
Sumario:The aim of the present study was to evaluate qualitative changes in the glycoconjugate expression in human gastric tissue of positive and negative patients for Helicobacter pylori, through lectins: Wheat Germ Agglutinin (WGA) and Concanavalin A (Con A). The lectins recognized differently the glycoconjugates in the superficial mucous layer at the gastric tissues. The results suggest a significant change in the carbohydrate moieties present on the surface of the gastric cells during infection.

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