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Influence of probiotics on Candida presence and IgA anti-Candida in the oral cavity
Probiotics are defined as microorganisms that promote benefits to host health, mainly by regulating resident microbiota. Disequilibrium in microbiota can favor the growth of opportunist microorganisms and the development of pathologies, like candidosis caused by yeasts of the Candida genus. This wor...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Microbiologia
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768569/ https://www.ncbi.nlm.nih.gov/pubmed/24031447 http://dx.doi.org/10.1590/S1517-838220090004000030 |
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author | dos Santos, Agda Lima Jorge, Antônio Olavo Cardoso dos Santos, Silvana Soléo Ferreira Silva, Célia Regina Gonçalves e Leão, Mariella Vieira Pereira |
author_facet | dos Santos, Agda Lima Jorge, Antônio Olavo Cardoso dos Santos, Silvana Soléo Ferreira Silva, Célia Regina Gonçalves e Leão, Mariella Vieira Pereira |
author_sort | dos Santos, Agda Lima |
collection | PubMed |
description | Probiotics are defined as microorganisms that promote benefits to host health, mainly by regulating resident microbiota. Disequilibrium in microbiota can favor the growth of opportunist microorganisms and the development of pathologies, like candidosis caused by yeasts of the Candida genus. This work evaluated whether probiotics consumption was able to influence a specific immunological response to Candida and the presence of these yeasts in the oral cavity. Saliva samples were collected from healthy individuals and plated in Dextrose Saboraud Agar with chloramphenicol. Individuals presenting Candida in the oral cavity used the probiotic Yakult LB® for 20 days, after which new collections and identifications were performed. Anti-Candida IgA analysis was conducted using the ELISA technique. Analysis of the results showed a significant reduction in Candida prevalence (46%) and mean Candida CFU/mL counts (65%). The Candida species identified were C. albicans (98%) and C. tropicalis (2%), before and after probiotics consumption. Immunological analysis demonstrated a significant reduction in anti-Candida IgA levels after probiotics use, probably due to less antigenic stimulation. In conclusion, in the individuals studied, probiotics use significantly reduced the amount of Candida in the oral cavity, possibly due to competition between the yeasts rather than by specific secretory immune response stimulation. |
format | Online Article Text |
id | pubmed-3768569 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Sociedade Brasileira de Microbiologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-37685692013-09-12 Influence of probiotics on Candida presence and IgA anti-Candida in the oral cavity dos Santos, Agda Lima Jorge, Antônio Olavo Cardoso dos Santos, Silvana Soléo Ferreira Silva, Célia Regina Gonçalves e Leão, Mariella Vieira Pereira Braz J Microbiol Medical Microbiology Probiotics are defined as microorganisms that promote benefits to host health, mainly by regulating resident microbiota. Disequilibrium in microbiota can favor the growth of opportunist microorganisms and the development of pathologies, like candidosis caused by yeasts of the Candida genus. This work evaluated whether probiotics consumption was able to influence a specific immunological response to Candida and the presence of these yeasts in the oral cavity. Saliva samples were collected from healthy individuals and plated in Dextrose Saboraud Agar with chloramphenicol. Individuals presenting Candida in the oral cavity used the probiotic Yakult LB® for 20 days, after which new collections and identifications were performed. Anti-Candida IgA analysis was conducted using the ELISA technique. Analysis of the results showed a significant reduction in Candida prevalence (46%) and mean Candida CFU/mL counts (65%). The Candida species identified were C. albicans (98%) and C. tropicalis (2%), before and after probiotics consumption. Immunological analysis demonstrated a significant reduction in anti-Candida IgA levels after probiotics use, probably due to less antigenic stimulation. In conclusion, in the individuals studied, probiotics use significantly reduced the amount of Candida in the oral cavity, possibly due to competition between the yeasts rather than by specific secretory immune response stimulation. Sociedade Brasileira de Microbiologia 2009 2009-12-01 /pmc/articles/PMC3768569/ /pubmed/24031447 http://dx.doi.org/10.1590/S1517-838220090004000030 Text en © Sociedade Brasileira de Microbiologia http://creativecommons.org/licenses/by-nc/3.0/ All the content of the journal, except where otherwise noted, is licensed under a Creative Commons License |
spellingShingle | Medical Microbiology dos Santos, Agda Lima Jorge, Antônio Olavo Cardoso dos Santos, Silvana Soléo Ferreira Silva, Célia Regina Gonçalves e Leão, Mariella Vieira Pereira Influence of probiotics on Candida presence and IgA anti-Candida in the oral cavity |
title | Influence of probiotics on Candida presence and IgA anti-Candida in the oral cavity |
title_full | Influence of probiotics on Candida presence and IgA anti-Candida in the oral cavity |
title_fullStr | Influence of probiotics on Candida presence and IgA anti-Candida in the oral cavity |
title_full_unstemmed | Influence of probiotics on Candida presence and IgA anti-Candida in the oral cavity |
title_short | Influence of probiotics on Candida presence and IgA anti-Candida in the oral cavity |
title_sort | influence of probiotics on candida presence and iga anti-candida in the oral cavity |
topic | Medical Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768569/ https://www.ncbi.nlm.nih.gov/pubmed/24031447 http://dx.doi.org/10.1590/S1517-838220090004000030 |
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