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Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies
The aim of the present study was to evaluate the antifungal susceptibility profile of Trichosporon species isolated from different sources employing the Clinical and Laboratory Standards Institute (CLSI) method and E-test method. Thirty-four isolates of Trichosporon spp. and six CBS reference sample...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Microbiologia
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768694/ https://www.ncbi.nlm.nih.gov/pubmed/24031497 http://dx.doi.org/10.1590/S1517-83822010000200008 |
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author | Lemes, Raquel M.L. Lyon, Juliana P. Moreira, Leonardo M. de Resende, Maria Aparecida |
author_facet | Lemes, Raquel M.L. Lyon, Juliana P. Moreira, Leonardo M. de Resende, Maria Aparecida |
author_sort | Lemes, Raquel M.L. |
collection | PubMed |
description | The aim of the present study was to evaluate the antifungal susceptibility profile of Trichosporon species isolated from different sources employing the Clinical and Laboratory Standards Institute (CLSI) method and E-test method. Thirty-four isolates of Trichosporon spp. and six CBS reference samples were tested for their susceptibility to Amphotericin B, 5-flucytosine, Fluconazole, Itraconazole, Voriconazole and Terbinafine. All species showed high Minimun Inhibitory Concentrations (MIC) for Itraconazole and susceptibility to Fluconazole, The comparison among the results obtained by the CLSI method and E-test revealed larger discrepancies among 5-flucytosine and Itraconazole. The present work provides epidemiological data that could influence therapeutic choices. Furthermore, the comparison between different methodologies could help to analyze results obtained by different laboratories. |
format | Online Article Text |
id | pubmed-3768694 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Sociedade Brasileira de Microbiologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-37686942013-09-12 Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies Lemes, Raquel M.L. Lyon, Juliana P. Moreira, Leonardo M. de Resende, Maria Aparecida Braz J Microbiol Medical Microbiology The aim of the present study was to evaluate the antifungal susceptibility profile of Trichosporon species isolated from different sources employing the Clinical and Laboratory Standards Institute (CLSI) method and E-test method. Thirty-four isolates of Trichosporon spp. and six CBS reference samples were tested for their susceptibility to Amphotericin B, 5-flucytosine, Fluconazole, Itraconazole, Voriconazole and Terbinafine. All species showed high Minimun Inhibitory Concentrations (MIC) for Itraconazole and susceptibility to Fluconazole, The comparison among the results obtained by the CLSI method and E-test revealed larger discrepancies among 5-flucytosine and Itraconazole. The present work provides epidemiological data that could influence therapeutic choices. Furthermore, the comparison between different methodologies could help to analyze results obtained by different laboratories. Sociedade Brasileira de Microbiologia 2010 2010-06-01 /pmc/articles/PMC3768694/ /pubmed/24031497 http://dx.doi.org/10.1590/S1517-83822010000200008 Text en © Sociedade Brasileira de Microbiologia http://creativecommons.org/licenses/by-nc/3.0/ All the content of the journal, except where otherwise noted, is licensed under a Creative Commons License |
spellingShingle | Medical Microbiology Lemes, Raquel M.L. Lyon, Juliana P. Moreira, Leonardo M. de Resende, Maria Aparecida Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies |
title | Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies |
title_full | Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies |
title_fullStr | Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies |
title_full_unstemmed | Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies |
title_short | Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies |
title_sort | antifungal susceptibility profile of trichosporon isolates: correlation between clsi and etest methodologies |
topic | Medical Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768694/ https://www.ncbi.nlm.nih.gov/pubmed/24031497 http://dx.doi.org/10.1590/S1517-83822010000200008 |
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