Peptidoglycan from Staphylococcus aureus induces the overexpression of TRLs 1–8 mRNA in corneal fibroblasts, but its lipoteichoic acid and muramyl dipeptide only induced the overexpression of TLR5 or TRL9

Lipopolysaccharide induces TLR-1–8 mRNAs over-expression in corneal fibroblast. Analyzing if other TLR-ligands can do the same, we found that peptidoglycan does, but not muramyldipeptide, lipoteichoic acid and polyI:C. This suggests that the recognition of lipopolysaccharide and peptidoglycan is eno...

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Autores principales: guez-Martínez, Sandra Rodrí, Sánchez-Zauco, Norma A., González-Ramírez, Ivonne, Cancino-Diaz, Juan C., Cancino-Diaz, Mario E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Microbiologia 2011
Materias:
Medical Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768798/
https://www.ncbi.nlm.nih.gov/pubmed/24031722
http://dx.doi.org/10.1590/S1517-838220110003000025
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author guez-Martínez, Sandra Rodrí
Sánchez-Zauco, Norma A.
González-Ramírez, Ivonne
Cancino-Diaz, Juan C.
Cancino-Diaz, Mario E.
author_facet guez-Martínez, Sandra Rodrí
Sánchez-Zauco, Norma A.
González-Ramírez, Ivonne
Cancino-Diaz, Juan C.
Cancino-Diaz, Mario E.
author_sort guez-Martínez, Sandra Rodrí
collection PubMed
description Lipopolysaccharide induces TLR-1–8 mRNAs over-expression in corneal fibroblast. Analyzing if other TLR-ligands can do the same, we found that peptidoglycan does, but not muramyldipeptide, lipoteichoic acid and polyI:C. This suggests that the recognition of lipopolysaccharide and peptidoglycan is enough to alert these cells against microorganisms through the over-expression of the majority TLRs.
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spelling pubmed-37687982013-09-12 Peptidoglycan from Staphylococcus aureus induces the overexpression of TRLs 1–8 mRNA in corneal fibroblasts, but its lipoteichoic acid and muramyl dipeptide only induced the overexpression of TLR5 or TRL9 guez-Martínez, Sandra Rodrí Sánchez-Zauco, Norma A. González-Ramírez, Ivonne Cancino-Diaz, Juan C. Cancino-Diaz, Mario E. Braz J Microbiol Medical Microbiology Lipopolysaccharide induces TLR-1–8 mRNAs over-expression in corneal fibroblast. Analyzing if other TLR-ligands can do the same, we found that peptidoglycan does, but not muramyldipeptide, lipoteichoic acid and polyI:C. This suggests that the recognition of lipopolysaccharide and peptidoglycan is enough to alert these cells against microorganisms through the over-expression of the majority TLRs. Sociedade Brasileira de Microbiologia 2011 2011-09-01 /pmc/articles/PMC3768798/ /pubmed/24031722 http://dx.doi.org/10.1590/S1517-838220110003000025 Text en © Sociedade Brasileira de Microbiologia http://creativecommons.org/licenses/by-nc/3.0/ All the content of the journal, except where otherwise noted, is licensed under a Creative Commons License
spellingShingle Medical Microbiology
guez-Martínez, Sandra Rodrí
Sánchez-Zauco, Norma A.
González-Ramírez, Ivonne
Cancino-Diaz, Juan C.
Cancino-Diaz, Mario E.
Peptidoglycan from Staphylococcus aureus induces the overexpression of TRLs 1–8 mRNA in corneal fibroblasts, but its lipoteichoic acid and muramyl dipeptide only induced the overexpression of TLR5 or TRL9
title Peptidoglycan from Staphylococcus aureus induces the overexpression of TRLs 1–8 mRNA in corneal fibroblasts, but its lipoteichoic acid and muramyl dipeptide only induced the overexpression of TLR5 or TRL9
title_full Peptidoglycan from Staphylococcus aureus induces the overexpression of TRLs 1–8 mRNA in corneal fibroblasts, but its lipoteichoic acid and muramyl dipeptide only induced the overexpression of TLR5 or TRL9
title_fullStr Peptidoglycan from Staphylococcus aureus induces the overexpression of TRLs 1–8 mRNA in corneal fibroblasts, but its lipoteichoic acid and muramyl dipeptide only induced the overexpression of TLR5 or TRL9
title_full_unstemmed Peptidoglycan from Staphylococcus aureus induces the overexpression of TRLs 1–8 mRNA in corneal fibroblasts, but its lipoteichoic acid and muramyl dipeptide only induced the overexpression of TLR5 or TRL9
title_short Peptidoglycan from Staphylococcus aureus induces the overexpression of TRLs 1–8 mRNA in corneal fibroblasts, but its lipoteichoic acid and muramyl dipeptide only induced the overexpression of TLR5 or TRL9
title_sort peptidoglycan from staphylococcus aureus induces the overexpression of trls 1–8 mrna in corneal fibroblasts, but its lipoteichoic acid and muramyl dipeptide only induced the overexpression of tlr5 or trl9
topic Medical Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768798/
https://www.ncbi.nlm.nih.gov/pubmed/24031722
http://dx.doi.org/10.1590/S1517-838220110003000025
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