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Diphtheria Antibodies and T lymphocyte Counts in Patients Infected With HIV-1

We assessed the IgG levels anti-diphtheria (D-Ab) and T cell counts (CD4+ and CD8+) in HIV-1 infected subjects undergoing or not highly active antiretroviral therapy (HAART). Approximately 70% of all HIV-1 patients were unprotected against diphtheria. There were no differences in D-Ab according to C...

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Autores principales: Speranza, Francisco A. B., Ishii, Solange K., Thuler, Luiz C. S., Damasco, Paulo V., Jr, Raphael Hirata, Mattos-Guaraldi, Ana L., Milagres, Lucimar G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Microbiologia 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768853/
https://www.ncbi.nlm.nih.gov/pubmed/24031911
http://dx.doi.org/10.1590/S1517-838220120003000014
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author Speranza, Francisco A. B.
Ishii, Solange K.
Thuler, Luiz C. S.
Damasco, Paulo V.
Jr, Raphael Hirata
Mattos-Guaraldi, Ana L.
Milagres, Lucimar G.
author_facet Speranza, Francisco A. B.
Ishii, Solange K.
Thuler, Luiz C. S.
Damasco, Paulo V.
Jr, Raphael Hirata
Mattos-Guaraldi, Ana L.
Milagres, Lucimar G.
author_sort Speranza, Francisco A. B.
collection PubMed
description We assessed the IgG levels anti-diphtheria (D-Ab) and T cell counts (CD4+ and CD8+) in HIV-1 infected subjects undergoing or not highly active antiretroviral therapy (HAART). Approximately 70% of all HIV-1 patients were unprotected against diphtheria. There were no differences in D-Ab according to CD4 counts. Untreated patients had higher D-Ab (geometric mean of 0.62 IU/ml) than HAART-patients (geometric mean of 0.39 IU/ml). The data indicated the necessity of keeping all HIV-1 patients up-to-date with their vaccination.
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spelling pubmed-37688532013-09-12 Diphtheria Antibodies and T lymphocyte Counts in Patients Infected With HIV-1 Speranza, Francisco A. B. Ishii, Solange K. Thuler, Luiz C. S. Damasco, Paulo V. Jr, Raphael Hirata Mattos-Guaraldi, Ana L. Milagres, Lucimar G. Braz J Microbiol Medical Microbiology We assessed the IgG levels anti-diphtheria (D-Ab) and T cell counts (CD4+ and CD8+) in HIV-1 infected subjects undergoing or not highly active antiretroviral therapy (HAART). Approximately 70% of all HIV-1 patients were unprotected against diphtheria. There were no differences in D-Ab according to CD4 counts. Untreated patients had higher D-Ab (geometric mean of 0.62 IU/ml) than HAART-patients (geometric mean of 0.39 IU/ml). The data indicated the necessity of keeping all HIV-1 patients up-to-date with their vaccination. Sociedade Brasileira de Microbiologia 2012 2012-06-01 /pmc/articles/PMC3768853/ /pubmed/24031911 http://dx.doi.org/10.1590/S1517-838220120003000014 Text en © Sociedade Brasileira de Microbiologia http://creativecommons.org/licenses/by-nc/3.0/ All the content of the journal, except where otherwise noted, is licensed under a Creative Commons License
spellingShingle Medical Microbiology
Speranza, Francisco A. B.
Ishii, Solange K.
Thuler, Luiz C. S.
Damasco, Paulo V.
Jr, Raphael Hirata
Mattos-Guaraldi, Ana L.
Milagres, Lucimar G.
Diphtheria Antibodies and T lymphocyte Counts in Patients Infected With HIV-1
title Diphtheria Antibodies and T lymphocyte Counts in Patients Infected With HIV-1
title_full Diphtheria Antibodies and T lymphocyte Counts in Patients Infected With HIV-1
title_fullStr Diphtheria Antibodies and T lymphocyte Counts in Patients Infected With HIV-1
title_full_unstemmed Diphtheria Antibodies and T lymphocyte Counts in Patients Infected With HIV-1
title_short Diphtheria Antibodies and T lymphocyte Counts in Patients Infected With HIV-1
title_sort diphtheria antibodies and t lymphocyte counts in patients infected with hiv-1
topic Medical Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768853/
https://www.ncbi.nlm.nih.gov/pubmed/24031911
http://dx.doi.org/10.1590/S1517-838220120003000014
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