Nitrate reductase assay using sodium nitrate for rapid detection of multidrug resistant tuberculosis

We validated the nitrate reductase assay (NRA) for the detection of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) using sodium nitrate (NaNO(3)) in replacement of potassium nitrate (KNO(3)) as nitrate source. NaNO(3) is cheaper than KNO(3) and has no restriction on use which facilitates th...

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Detalles Bibliográficos
Autores principales: Macedo, Maíra Bidart, Groll, Andrea Von, Fissette, Krista, Palomino, Juan Carlos, da Silva, Pedro Eduardo Almeida, Martin, Anandi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Microbiologia 2012
Materias:
Medical Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768877/
https://www.ncbi.nlm.nih.gov/pubmed/24031916
http://dx.doi.org/10.1590/S1517-838220120003000019
Descripción
Sumario:We validated the nitrate reductase assay (NRA) for the detection of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) using sodium nitrate (NaNO(3)) in replacement of potassium nitrate (KNO(3)) as nitrate source. NaNO(3) is cheaper than KNO(3) and has no restriction on use which facilitates the implementation of NRA to detect MDR-TB.

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