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Processing of projections containing phase contrast in laboratory micro-computerized tomography imaging

Free-space-propagation-based imaging belongs to several techniques for achieving phase contrast in the hard X-ray range. The basic precondition is to use an X-ray beam with a high degree of coherence. Although the best sources of coherent X-rays are synchrotrons, spatially coherent X-rays emitted fr...

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Autores principales: Zápražný, Zdenko, Korytár, Dušan, Mikulík, Petr, Áč, Vladimír
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769065/
https://www.ncbi.nlm.nih.gov/pubmed/24046501
http://dx.doi.org/10.1107/S002188981300558X
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author Zápražný, Zdenko
Korytár, Dušan
Mikulík, Petr
Áč, Vladimír
author_facet Zápražný, Zdenko
Korytár, Dušan
Mikulík, Petr
Áč, Vladimír
author_sort Zápražný, Zdenko
collection PubMed
description Free-space-propagation-based imaging belongs to several techniques for achieving phase contrast in the hard X-ray range. The basic precondition is to use an X-ray beam with a high degree of coherence. Although the best sources of coherent X-rays are synchrotrons, spatially coherent X-rays emitted from a sufficiently small spot of laboratory microfocus or sub-microfocus sources allow the transfer of some of the modern imaging techniques from synchrotrons to laboratories. Spatially coherent X-rays traverse a sample leading to a phase shift. Beam deflection induced by the local change of refractive index may be expressed as a dark–bright contrast on the edges of the object in an X-ray projection. This phenomenon of edge enhancement leads to an increase in spatial resolution of X-ray projections but may also lead to unpleasant artefacts in computerized tomography unless phase and absorption contributions are separated. The possibilities of processing X-ray images of lightweight objects containing phase contrast using phase-retrieval methods in laboratory conditions are tested and the results obtained are presented. For this purpose, simulated and recorded X-ray projections taken from a laboratory imaging system with a microfocus X-ray source and a high-resolution CCD camera were processed and a qualitative comparison of results was made.
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spelling pubmed-37690652013-09-17 Processing of projections containing phase contrast in laboratory micro-computerized tomography imaging Zápražný, Zdenko Korytár, Dušan Mikulík, Petr Áč, Vladimír J Appl Crystallogr X-Ray Diffraction and Imaging Free-space-propagation-based imaging belongs to several techniques for achieving phase contrast in the hard X-ray range. The basic precondition is to use an X-ray beam with a high degree of coherence. Although the best sources of coherent X-rays are synchrotrons, spatially coherent X-rays emitted from a sufficiently small spot of laboratory microfocus or sub-microfocus sources allow the transfer of some of the modern imaging techniques from synchrotrons to laboratories. Spatially coherent X-rays traverse a sample leading to a phase shift. Beam deflection induced by the local change of refractive index may be expressed as a dark–bright contrast on the edges of the object in an X-ray projection. This phenomenon of edge enhancement leads to an increase in spatial resolution of X-ray projections but may also lead to unpleasant artefacts in computerized tomography unless phase and absorption contributions are separated. The possibilities of processing X-ray images of lightweight objects containing phase contrast using phase-retrieval methods in laboratory conditions are tested and the results obtained are presented. For this purpose, simulated and recorded X-ray projections taken from a laboratory imaging system with a microfocus X-ray source and a high-resolution CCD camera were processed and a qualitative comparison of results was made. International Union of Crystallography 2013-08-01 2013-06-07 /pmc/articles/PMC3769065/ /pubmed/24046501 http://dx.doi.org/10.1107/S002188981300558X Text en © Zdenko Zápražný et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle X-Ray Diffraction and Imaging
Zápražný, Zdenko
Korytár, Dušan
Mikulík, Petr
Áč, Vladimír
Processing of projections containing phase contrast in laboratory micro-computerized tomography imaging
title Processing of projections containing phase contrast in laboratory micro-computerized tomography imaging
title_full Processing of projections containing phase contrast in laboratory micro-computerized tomography imaging
title_fullStr Processing of projections containing phase contrast in laboratory micro-computerized tomography imaging
title_full_unstemmed Processing of projections containing phase contrast in laboratory micro-computerized tomography imaging
title_short Processing of projections containing phase contrast in laboratory micro-computerized tomography imaging
title_sort processing of projections containing phase contrast in laboratory micro-computerized tomography imaging
topic X-Ray Diffraction and Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769065/
https://www.ncbi.nlm.nih.gov/pubmed/24046501
http://dx.doi.org/10.1107/S002188981300558X
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