Cargando…

Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1(−/−) mice

BACKGROUND: Complex interactions involving genetic susceptibility and environmental factors are thought to underlie the pathogenesis of Parkinson’s disease (PD). Although the role of inflammatory processes in modulating risk for development of PD has yet to be fully understood, prospective studies s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nguyen, Thi A, Frank-Cannon, Tamy, Martinez, Terina N, Ruhn, Kelly A, Marvin, Marian, Casey, Bradford, Treviño, Isaac, Hong, John J, Goldberg, Matthew S, Tansey, Malú G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769147/ https://www.ncbi.nlm.nih.gov/pubmed/23622116 http://dx.doi.org/10.1186/1742-2094-10-50

Ejemplares similares

AAV-Dominant Negative Tumor Necrosis Factor (DN-TNF) Gene Transfer to the Striatum Does Not Rescue Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease
por: Alto, Laura Taylor, et al.
Publicado: (2014)

The Neuro-Glial Properties of Adipose-Derived Adult Stromal (ADAS) Cells Are Not Regulated by Notch 1 and Are Not Derived from Neural Crest Lineage
por: Wrage, Philip C., et al.
Publicado: (2008)

Behavioral and Neurotransmitter Abnormalities in Mice Deficient for Parkin, DJ-1 and Superoxide Dismutase
por: Hennis, Meghan R., et al.
Publicado: (2013)

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration
por: Duffy, Megan F., et al.
Publicado: (2018)

Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration
por: Duffy, Megan F., et al.
Publicado: (2018)

Does neuroinflammation fan the flame in neurodegenerative diseases?
por: Frank-Cannon, Tamy C, et al.
Publicado: (2009)

Aging Reveals a Role for Nigral Tyrosine Hydroxylase ser31 Phosphorylation in Locomotor Activity Generation
por: Salvatore, Michael F., et al.
Publicado: (2009)

Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons
por: Benner, Eric J., et al.
Publicado: (2008)

Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons
por: Garrido, Manuel, et al.
Publicado: (2010)

Multi-facetted impulsivity following nigral degeneration and dopamine replacement therapy
por: Engeln, Michel, et al.
Publicado: (2016)

Ceramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons
por: Martinez, Terina N, et al.
Publicado: (2012)

Reintroduction of DJ-1 in Müller Cells Inhibits Retinal Degeneration in the DJ-1 Deficient Retina
por: Gharbi, Naouel, et al.
Publicado: (2021)

Nigral Neurons Degenerating in Parkinson's Disease Express the Angiotensin Receptor Type 1 Gene
por: Labandeira‐Garcia, Jose L., et al.
Publicado: (2022)

DJ1 at the interface between neuro-degeneration and cancer
por: Meiser, Johannes, et al.
Publicado: (2017)

An imbalance of netrin‐1 and DCC during nigral degeneration in experimental models and patients with Parkinson's disease
por: Hua, Ye, et al.
Publicado: (2023)

The gut-brain axis: is intestinal inflammation a silent driver of Parkinson’s disease pathogenesis?
por: Houser, Madelyn C., et al.
Publicado: (2017)

DJ-1 contributes to adipogenesis and obesity-induced inflammation
por: Kim, Jung-Min, et al.
Publicado: (2014)

Nigral iron deposition in common tremor disorders
por: Homayoon, Nina, et al.
Publicado: (2018)

Discovery of nigral dopaminergic neurogenesis in adult mice
por: Morrison, Brad E.
Publicado: (2016)

Height and nigral neuron density in Parkinson’s disease
por: Saari, Laura, et al.
Publicado: (2022)

Microfluidics-free single-cell genomics reveals complex central-peripheral immune crosstalk in the mouse brain during peripheral inflammation
por: Tansey, Malú, et al.
Publicado: (2023)

Anti-oxidant polydatin (piceid) protects against substantia nigral motor degeneration in multiple rodent models of Parkinson’s disease
por: Chen, Yupin, et al.
Publicado: (2015)

Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis
por: Staats, Kim A., et al.
Publicado: (2022)

Extracellular DJ-1 induces sterile inflammation in the ischemic brain
por: Nakamura, Koutarou, et al.
Publicado: (2021)

Transcriptional Activation of Low-Density Lipoprotein Receptor Gene by DJ-1 and Effect of DJ-1 on Cholesterol Homeostasis
por: Yamaguchi, Shiori, et al.
Publicado: (2012)

Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice
por: Yamaguchi, Hiroo, et al.
Publicado: (2007)

Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation
por: de Pablos, Rocío M, et al.
Publicado: (2014)

Lipopolysaccharide and Tumor Necrosis Factor Regulate Parkin Expression via Nuclear Factor-Kappa B
por: Tran, Thi A., et al.
Publicado: (2011)

Progranulin and GPNMB: interactions in endo-lysosome function and inflammation in neurodegenerative disease
por: Gillett, Drew A., et al.
Publicado: (2023)

The contribution of Parkin, PINK1 and DJ‐1 genes to selective neuronal degeneration in Parkinson's disease
por: van der Vlag, Marc, et al.
Publicado: (2020)

Protection of nigral dopaminergic neurons by AAV1 transduction with Rheb(S16H) against neurotoxic inflammation in vivo
por: Kim, Sehwan, et al.
Publicado: (2018)

Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease
por: García-Domínguez, Irene, et al.
Publicado: (2018)

The Mobile DJ Handbook
por: Zemon, Stacy
Publicado: (2013)

DJ Ethics and Law
Publicado: (2022)

Impact of age and vector construct on striatal and nigral transgene expression
por: Polinski, Nicole K, et al.
Publicado: (2016)

Effects of Subthalamic and Nigral Stimulation on Gait Kinematics in Parkinson’s Disease
por: Scholten, Marlieke, et al.
Publicado: (2017)

Reversing Parkinson Disease Model with in situ Converted Nigral Neurons
por: Qian, Hao, et al.
Publicado: (2020)

Impact of simultaneous subthalamic and nigral stimulation on dysphagia in Parkinson’s disease
por: Pflug, Christina, et al.
Publicado: (2020)

Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease
por: Heilman, Patrick L., et al.
Publicado: (2020)

Subthalamic and nigral neurons are differentially modulated during parkinsonian gait
por: Gulberti, Alessandro, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nj0421l2409q3ap17ifamphp30