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The AP-1 Transcription Factor c-Jun Prevents Stress-Imposed Maladaptive Remodeling of the Heart

Systemic hypertension increases cardiac workload and subsequently induces signaling networks in heart that underlie myocyte growth (hypertrophic response) through expansion of sarcomeres with the aim to increase contractility. However, conditions of increased workload can induce both adaptive and ma...

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Detalles Bibliográficos
Autores principales: Windak, Renata, Müller, Julius, Felley, Allison, Akhmedov, Alexander, Wagner, Erwin F., Pedrazzini, Thierry, Sumara, Grzegorz, Ricci, Romeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769267/
https://www.ncbi.nlm.nih.gov/pubmed/24039904
http://dx.doi.org/10.1371/journal.pone.0073294

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