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Identification of an Evolutionarily Conserved Cis-Regulatory Element Controlling the Peg3 Imprinted Domain
The mammalian Peg3 domain harbors more than 20 evolutionarily conserved regions (ECRs) that are spread over the 250-kb genomic interval. The majority of these ECRs are marked with two histone modifications, H3K4me1 and H3K27ac, suggesting potential roles as distant regulatory elements for the transc...
Autores principales: | Thiaville, Michelle M., Kim, Hana, Frey, Wesley D., Kim, Joomyeong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769284/ https://www.ncbi.nlm.nih.gov/pubmed/24040411 http://dx.doi.org/10.1371/journal.pone.0075417 |
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