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Fate of Pup inside the Mycobacterium Proteasome Studied by in-Cell NMR
The Mycobacterium tuberculosis proteasome is required for maximum virulence and to resist killing by the host immune system. The prokaryotic ubiquitin-like protein, Pup-GGE, targets proteins for proteasome-mediated degradation. We demonstrate that Pup-GGQ, a precursor of Pup-GGE, is not a substrate...
Autores principales: | Maldonado, Andres Y., Burz, David S., Reverdatto, Sergey, Shekhtman, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769308/ https://www.ncbi.nlm.nih.gov/pubmed/24040288 http://dx.doi.org/10.1371/journal.pone.0074576 |
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