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Zygotic G2/M Cell Cycle Arrest Induced by ATM/Chk1 Activation and DNA Repair in Mouse Embryos Fertilized with Hydrogen Peroxide-Treated Epididymal Mouse Sperm

Human sperm cryopreservation for assisted reproduction is compromised by ROS-induced sperm cryodamage. Our previous model study in which mouse sperm were treated with H(2)O(2) to simulate sperm DNA-damage caused by cryopreservation-induced ROS have discovered that mouse embryos fertilized with treat...

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Detalles Bibliográficos
Autores principales:	Wang, Bin, Li, Zhiling, Wang, Chao, Chen, Man, Xiao, Jianfeng, Wu, Xiaoyan, Xiao, Wanfen, Song, Yu, Wang, Xiaoyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769350/ https://www.ncbi.nlm.nih.gov/pubmed/24040138 http://dx.doi.org/10.1371/journal.pone.0073987

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