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Stochastic Simulation of Endemic Salmonella enterica Serovar Typhi: The Importance of Long Lasting Immunity and the Carrier State

BACKGROUND: Typhoid fever caused by Salmonella enterica serovar Typhi (S. Typhi) remains a serious burden of disease, especially in developing countries of Asia and Africa. It is estimated that it causes 200,000 deaths per year, mainly in children. S. Typhi is an obligate pathogen of humans and alth...

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Detalles Bibliográficos
Autores principales: Saul, Allan, Smith, Tom, Maire, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769365/
https://www.ncbi.nlm.nih.gov/pubmed/24040177
http://dx.doi.org/10.1371/journal.pone.0074097