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The Design and In Vivo Evaluation of Engineered I-OnuI-Based Enzymes for HEG Gene Drive
The homing endonuclease gene (HEG) drive system, a promising genetic approach for controlling arthropod populations, utilises engineered nucleases to spread deleterious mutations that inactivate individual genes throughout a target population. Previous work with a naturally occurring LAGLIDADG homin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769382/ https://www.ncbi.nlm.nih.gov/pubmed/24040217 http://dx.doi.org/10.1371/journal.pone.0074254 |