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Local proliferation dominates lesional macrophage accumulation in atherosclerosis

During the inflammatory response that drives atherogenesis, macrophages accumulate progressively in the expanding arterial wall(1,2). The observation that circulating monocytes give rise to lesional macrophages(3–9) has reinforced the concept that monocyte infiltration dictates macrophage build-up....

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Detalles Bibliográficos
Autores principales: Robbins, Clinton S., Hilgendorf, Ingo, Weber, Georg F., Theurl, Igor, Iwamoto, Yoshiko, Figueiredo, Jose-Luiz, Gorbatov, Rostic, Sukhova, Galina K., Gerhardt, Louisa M.S., Smyth, David, Zavitz, Caleb C. J., Shikatani, Eric A., Parsons, Michael, van Rooijen, Nico, Lin, Herbert Y., Husain, Mansoor, Libby, Peter, Nahrendorf, Matthias, Weissleder, Ralph, Swirski, Filip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769444/
https://www.ncbi.nlm.nih.gov/pubmed/23933982
http://dx.doi.org/10.1038/nm.3258