Structural and Functional Analysis of Giant Strong Component of Bacillus thuringiensis Metabolic Network

The purpose of this work was to study the giant strong component (GSC) of B. thuringiensis metabolic network by structural and functional analysis. Based on so-called “bow tie” structure, we extracted and studied GSC with its functional significance. Global structural properties such as degree distr...

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Detalles Bibliográficos
Autores principales: Ding, D.W., Ding, Y.R., Li, L.N., Cai, Y.J., Xu, W.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Microbiologia 2009
Materias:
General Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769732/
https://www.ncbi.nlm.nih.gov/pubmed/24031381
http://dx.doi.org/10.1590/S1517-838220090002000036
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author Ding, D.W.
Ding, Y.R.
Li, L.N.
Cai, Y.J.
Xu, W.B.
author_facet Ding, D.W.
Ding, Y.R.
Li, L.N.
Cai, Y.J.
Xu, W.B.
author_sort Ding, D.W.
collection PubMed
description The purpose of this work was to study the giant strong component (GSC) of B. thuringiensis metabolic network by structural and functional analysis. Based on so-called “bow tie” structure, we extracted and studied GSC with its functional significance. Global structural properties such as degree distribution and average path length were computed and indicated that the GSC is also a small-world and scale-free network. Furthermore, the GSC was decomposed and functional significant for metabolism of these divisions were investigated by comparing to KEGG metabolic pathways.
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spelling pubmed-37697322013-09-12 Structural and Functional Analysis of Giant Strong Component of Bacillus thuringiensis Metabolic Network Ding, D.W. Ding, Y.R. Li, L.N. Cai, Y.J. Xu, W.B. Braz J Microbiol General Microbiology The purpose of this work was to study the giant strong component (GSC) of B. thuringiensis metabolic network by structural and functional analysis. Based on so-called “bow tie” structure, we extracted and studied GSC with its functional significance. Global structural properties such as degree distribution and average path length were computed and indicated that the GSC is also a small-world and scale-free network. Furthermore, the GSC was decomposed and functional significant for metabolism of these divisions were investigated by comparing to KEGG metabolic pathways. Sociedade Brasileira de Microbiologia 2009 2009-06-01 /pmc/articles/PMC3769732/ /pubmed/24031381 http://dx.doi.org/10.1590/S1517-838220090002000036 Text en © Sociedade Brasileira de Microbiologia http://creativecommons.org/licenses/by-nc/3.0/ All the content of the journal, except where otherwise noted, is licensed under a Creative Commons License
spellingShingle General Microbiology
Ding, D.W.
Ding, Y.R.
Li, L.N.
Cai, Y.J.
Xu, W.B.
Structural and Functional Analysis of Giant Strong Component of Bacillus thuringiensis Metabolic Network
title Structural and Functional Analysis of Giant Strong Component of Bacillus thuringiensis Metabolic Network
title_full Structural and Functional Analysis of Giant Strong Component of Bacillus thuringiensis Metabolic Network
title_fullStr Structural and Functional Analysis of Giant Strong Component of Bacillus thuringiensis Metabolic Network
title_full_unstemmed Structural and Functional Analysis of Giant Strong Component of Bacillus thuringiensis Metabolic Network
title_short Structural and Functional Analysis of Giant Strong Component of Bacillus thuringiensis Metabolic Network
title_sort structural and functional analysis of giant strong component of bacillus thuringiensis metabolic network
topic General Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769732/
https://www.ncbi.nlm.nih.gov/pubmed/24031381
http://dx.doi.org/10.1590/S1517-838220090002000036
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