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Optimization of clavulanic acid production by Streptomyces daufpe 3060 by response surface methodology

Clavulanic acid is a ß-lactam antibiotic which has a potent ß-lactamase inhibiting activity. In order to optimize its production by the new isolate Streptomyces DAUFPE 3060, the influence of two independent variables, temperature and soybean flour concentration, on clavulanic acid and biomass concen...

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Detalles Bibliográficos
Autores principales:	Marques, Daniela A. Viana, Cunha, Márcia N. Carneiro, Araújo, Janete M., Lima-Filho, José L., Converti, Attilio, Pessoa-Jr, Adalberto, Porto, Ana L. Figueiredo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Microbiologia 2011
Materias:	Industrial Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769858/ https://www.ncbi.nlm.nih.gov/pubmed/24031677 http://dx.doi.org/10.1590/S1517-838220110002000030

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