Neonatal Natural Killer Cell Function: Relevance to Antiviral Immune Defense

Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phe...

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Detalles Bibliográficos
Autores principales: Lee, Yen-Chang, Lin, Syh-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770027/
https://www.ncbi.nlm.nih.gov/pubmed/24066005
http://dx.doi.org/10.1155/2013/427696
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author Lee, Yen-Chang
Lin, Syh-Jae
author_facet Lee, Yen-Chang
Lin, Syh-Jae
author_sort Lee, Yen-Chang
collection PubMed
description Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications.
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spelling pubmed-37700272013-09-24 Neonatal Natural Killer Cell Function: Relevance to Antiviral Immune Defense Lee, Yen-Chang Lin, Syh-Jae Clin Dev Immunol Review Article Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications. Hindawi Publishing Corporation 2013 2013-08-26 /pmc/articles/PMC3770027/ /pubmed/24066005 http://dx.doi.org/10.1155/2013/427696 Text en Copyright © 2013 Y.-C. Lee and S.-J. Lin. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Lee, Yen-Chang
Lin, Syh-Jae
Neonatal Natural Killer Cell Function: Relevance to Antiviral Immune Defense
title Neonatal Natural Killer Cell Function: Relevance to Antiviral Immune Defense
title_full Neonatal Natural Killer Cell Function: Relevance to Antiviral Immune Defense
title_fullStr Neonatal Natural Killer Cell Function: Relevance to Antiviral Immune Defense
title_full_unstemmed Neonatal Natural Killer Cell Function: Relevance to Antiviral Immune Defense
title_short Neonatal Natural Killer Cell Function: Relevance to Antiviral Immune Defense
title_sort neonatal natural killer cell function: relevance to antiviral immune defense
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770027/
https://www.ncbi.nlm.nih.gov/pubmed/24066005
http://dx.doi.org/10.1155/2013/427696
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AT linsyhjae neonatalnaturalkillercellfunctionrelevancetoantiviralimmunedefense

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