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ATF3 Protects against LPS-Induced Inflammation in Mice via Inhibiting HMGB1 Expression

Lipopolysaccharide (LPS) triggers innate immunity mainly via TLR4 signaling. ATF3 is a negative regulator of TLR4 signaling. HMGB1 plays a critical role in the final step of sepsis. However, the mechanisms of ATF3 and the role of HMGB1 in regulating innate immunity-induced sepsis are incompletely un...

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Detalles Bibliográficos
Autores principales:	Lai, Pei-Fang, Cheng, Ching-Feng, Lin, Heng, Tseng, Tzu-Ling, Chen, Hsi-Hsien, Chen, Sung-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770047/ https://www.ncbi.nlm.nih.gov/pubmed/24062788 http://dx.doi.org/10.1155/2013/716481

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