4-Bromo-2-[5-methyl-2-(morpholin-4-yl)-1,3-thia­zol-4-yl]phenol

In the title compound, C(14)H(15)BrN(2)O(2)S, synthesized by the reaction of the corresponding phenacyl thio­cyanate with morpholine, the dihedral angle between the 1,3-thia­zole ring and the phenolic substituent ring is 23.46 (10)° as a result of the steric influence of the ortho-methyl group on th...

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Detalles Bibliográficos
Autores principales: Bahrin, Lucian G., Hrib, Cristian G., Birsa, Lucian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770429/
https://www.ncbi.nlm.nih.gov/pubmed/24046714
http://dx.doi.org/10.1107/S1600536813017510
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author Bahrin, Lucian G.
Hrib, Cristian G.
Birsa, Lucian M.
author_facet Bahrin, Lucian G.
Hrib, Cristian G.
Birsa, Lucian M.
author_sort Bahrin, Lucian G.
collection PubMed
description In the title compound, C(14)H(15)BrN(2)O(2)S, synthesized by the reaction of the corresponding phenacyl thio­cyanate with morpholine, the dihedral angle between the 1,3-thia­zole ring and the phenolic substituent ring is 23.46 (10)° as a result of the steric influence of the ortho-methyl group on the thia­zole ring. A strong intra­molecular phenolic O—H⋯N hydrogen bond is present in the mol­ecule. In the crystal, a weak C—H⋯O(phenol) hydrogen bond gives rise to chains lying parallel to [20-1]. A short inter­molecular Br⋯O(morpholine) inter­action is also present [3.1338 (19) Å].
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spelling pubmed-37704292013-09-17 4-Bromo-2-[5-methyl-2-(morpholin-4-yl)-1,3-thia­zol-4-yl]phenol Bahrin, Lucian G. Hrib, Cristian G. Birsa, Lucian M. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(14)H(15)BrN(2)O(2)S, synthesized by the reaction of the corresponding phenacyl thio­cyanate with morpholine, the dihedral angle between the 1,3-thia­zole ring and the phenolic substituent ring is 23.46 (10)° as a result of the steric influence of the ortho-methyl group on the thia­zole ring. A strong intra­molecular phenolic O—H⋯N hydrogen bond is present in the mol­ecule. In the crystal, a weak C—H⋯O(phenol) hydrogen bond gives rise to chains lying parallel to [20-1]. A short inter­molecular Br⋯O(morpholine) inter­action is also present [3.1338 (19) Å]. International Union of Crystallography 2013-06-29 /pmc/articles/PMC3770429/ /pubmed/24046714 http://dx.doi.org/10.1107/S1600536813017510 Text en © Bahrin et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Bahrin, Lucian G.
Hrib, Cristian G.
Birsa, Lucian M.
4-Bromo-2-[5-methyl-2-(morpholin-4-yl)-1,3-thia­zol-4-yl]phenol
title 4-Bromo-2-[5-methyl-2-(morpholin-4-yl)-1,3-thia­zol-4-yl]phenol
title_full 4-Bromo-2-[5-methyl-2-(morpholin-4-yl)-1,3-thia­zol-4-yl]phenol
title_fullStr 4-Bromo-2-[5-methyl-2-(morpholin-4-yl)-1,3-thia­zol-4-yl]phenol
title_full_unstemmed 4-Bromo-2-[5-methyl-2-(morpholin-4-yl)-1,3-thia­zol-4-yl]phenol
title_short 4-Bromo-2-[5-methyl-2-(morpholin-4-yl)-1,3-thia­zol-4-yl]phenol
title_sort 4-bromo-2-[5-methyl-2-(morpholin-4-yl)-1,3-thia­zol-4-yl]phenol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770429/
https://www.ncbi.nlm.nih.gov/pubmed/24046714
http://dx.doi.org/10.1107/S1600536813017510
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