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Preparation and in vivo absorption evaluation of spray dried powders containing salmon calcitonin loaded chitosan nanoparticles for pulmonary delivery

PURPOSE: The aim of the present study was to prepare inhalable co-spray dried powders of salmon calcitonin loaded chitosan nanoparticles (sCT-CS-NPs) with mannitol and investigate pulmonary absorption in rats. METHODS: The sCT-CS-NPs were prepared by the ionic gelation method using sodium tripolypho...

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Detalles Bibliográficos
Autores principales:	Sinsuebpol, Chutima, Chatchawalsaisin, Jittima, Kulvanich, Poj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770519/ https://www.ncbi.nlm.nih.gov/pubmed/24039397 http://dx.doi.org/10.2147/DDDT.S47681

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