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DNA Topoisomerases Participate in Fragility of the Oncogene RET

Fragile site breakage was previously shown to result in rearrangement of the RET oncogene, resembling the rearrangements found in thyroid cancer. Common fragile sites are specific regions of the genome with a high susceptibility to DNA breakage under conditions that partially inhibit DNA replication...

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Detalles Bibliográficos
Autores principales:	Dillon, Laura W., Pierce, Levi C. T., Lehman, Christine E., Nikiforov, Yuri E., Wang, Yuh-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770543/ https://www.ncbi.nlm.nih.gov/pubmed/24040417 http://dx.doi.org/10.1371/journal.pone.0075741

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