Multicompartmental Pharmacokinetic Model of Tenofovir Delivery by a Vaginal Gel

BACKGROUND: Trials of a vaginal Tenofovir gel for pre-exposure prophylaxis (PrEP) for HIV have given conflicting results. Knowledge of concentrations of Tenofovir and its active form Tenofovir diphosphate, at putative sites of anti-HIV functioning, is central to understanding trial outcomes and desi...

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Detalles Bibliográficos
Autores principales: Gao, Yajing, Katz, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770582/
https://www.ncbi.nlm.nih.gov/pubmed/24040241
http://dx.doi.org/10.1371/journal.pone.0074404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770582/
https://www.ncbi.nlm.nih.gov/pubmed/24040241
http://dx.doi.org/10.1371/journal.pone.0074404

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