Simvastatin Induced Neurite Outgrowth Unveils Role of Cell Surface Cholesterol and Acetyl CoA Carboxylase in SH-SY5Y Cells

Statins are known to modulate cell surface cholesterol (CSC) and AMP-activated protein kinase (AMPK) in non-neural cells; however no study demonstrates whether CSC and AMPK may regulate simvastatin induced neuritogenesis (SIN). We found that simvastatin (SIM) maintains CSC as shown by Fillipin III s...

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Detalles Bibliográficos
Autores principales: Raina, Varshiesh, Gupta, Sarika, Yadav, Saurabh, Surolia, Avadhesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770597/
https://www.ncbi.nlm.nih.gov/pubmed/24040277
http://dx.doi.org/10.1371/journal.pone.0074547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770597/
https://www.ncbi.nlm.nih.gov/pubmed/24040277
http://dx.doi.org/10.1371/journal.pone.0074547

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