Regulation of FOXOs and p53 by SIRT1 Modulators under Oxidative Stress

Excessive reactive oxygen species (ROS) induce apoptosis and are associated with various diseases and with aging. SIRT1 (sirtuin-1), an NAD+-dependent protein deacetylase, decreases ROS levels and participates in cell survival under oxidative stress conditions. SIRT1 modulates the transcription fact...

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Detalles Bibliográficos
Autores principales: Hori, Yusuke S., Kuno, Atsushi, Hosoda, Ryusuke, Horio, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770600/
https://www.ncbi.nlm.nih.gov/pubmed/24040102
http://dx.doi.org/10.1371/journal.pone.0073875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770600/
https://www.ncbi.nlm.nih.gov/pubmed/24040102
http://dx.doi.org/10.1371/journal.pone.0073875

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