Anti-Cadherin-17 Antibody Modulates Beta-Catenin Signaling and Tumorigenicity of Hepatocellular Carcinoma

Cadherin-17 (CDH17) is an oncofetal molecule associated with poor prognostic outcomes of hepatocellular carcinoma (HCC), for which the treatment options are very limited. The present study investigates the therapeutic potential of a monoclonal antibody (Lic5) that targets the CDH17 antigen in HCC. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yonggang, Shek, Felix H., Wong, Kwong F., Liu, Ling Xiao, Zhang, Xiao Qian, Yuan, Yi, Khin, Ester, Hu, Mei-yu, Wang, Jian Hua, Poon, Ronnie T. P., Hong, Wanjin, Lee, Nikki P., Luk, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770615/
https://www.ncbi.nlm.nih.gov/pubmed/24039755
http://dx.doi.org/10.1371/journal.pone.0072386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770615/
https://www.ncbi.nlm.nih.gov/pubmed/24039755
http://dx.doi.org/10.1371/journal.pone.0072386

Ejemplares similares