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Development, clinical utility, and place of ivacaftor in the treatment of cystic fibrosis

Cystic fibrosis (CF) is a life-limiting, multisystem disease characterized by thick viscous secretions leading to recurrent lung infections, bronchiectasis, and progressive deterioration in lung function. CF is caused by loss or dysfunction of the CF transmembrane conductance regulator (CFTR) protei...

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Detalles Bibliográficos
Autores principales: O’Reilly, Ruth, Elphick, Heather E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770629/
https://www.ncbi.nlm.nih.gov/pubmed/24039402
http://dx.doi.org/10.2147/DDDT.S30345

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