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In Vitro Screening for Compounds That Enhance Human L1 Mobilization
The Long interspersed element 1 (LINE1 or L1) retrotransposon constitutes 17% of the human genome. There are currently 80–100 human L1 elements that are thought to be active in any diploid human genome. These elements can mobilize into new locations of the genome, resulting in changes in genomic inf...
Autores principales: | Terasaki, Natsuko, Goodier, John L., Cheung, Ling E., Wang, Yue J., Kajikawa, Masaki, Kazazian, Haig H., Okada, Norihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770661/ https://www.ncbi.nlm.nih.gov/pubmed/24040300 http://dx.doi.org/10.1371/journal.pone.0074629 |
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