The small molecule, genistein, increases hepcidin expression in human hepatocytes

Hepcidin, a peptide hormone that decreases intestinal iron absorption and macrophage iron release, is a potential drug target for patients with iron overload syndromes because its levels are inappropriately low in these individuals. Endogenous stimulants of Hepcidin transcription include bone morpho...

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Detalles Bibliográficos
Autores principales: Zhen, Aileen W, Nguyen, Nancy H, Gibert, Yann, Motola, Shmulik, Buckett, Peter, Wessling-Resnick, Marianne, Fraenkel, Ernest, Fraenkel, Paula G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Steatohepatitis/Metabolic Liver Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770762/
https://www.ncbi.nlm.nih.gov/pubmed/23703590
http://dx.doi.org/10.1002/hep.26490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770762/
https://www.ncbi.nlm.nih.gov/pubmed/23703590
http://dx.doi.org/10.1002/hep.26490

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